Therapeutic Effects of Cannabis and Cannabinoids
Relief from chronic pain is by far the most common condition cited by patients for the medical use of cannabis. For example, Light et al. (2014) reported that 94 percent of Colorado medical marijuana ID cardholders indicated “severe pain” as a medical condition. Likewise, Ilgen et al. (2013) reported that 87 percent of participants in their study were seeking medical marijuana for pain relief. In addition, there is evidence that some individuals are replacing the use of conventional pain medications (e.g., opiates) with cannabis. For example, one recent study reported survey data from patrons of a Michigan medical marijuana dispensary suggesting that medical cannabis use in pain patients was associated with a 64 percent reduction in opioid use (Boehnke et al., 2016).
Cannabidiol (CBD)-what we know
FIGHT CANCER
Using the committee's search strategy only one recent review was found to be of good to fair quality (Rocha et al., 2014).3 The review focused exclusively on the anti-tumor effects of cannabinoids on gliomas.
DEPRESSION
Depression is one of the nation's most common mental health disorders (ADAA, 2016). Across the many depressive disorders that exist (e.g., persistent depressive disorder, major depressive disorder, premenstrual dysphoric disorder) there are common symptomatic features of feelings of sadness, emptiness, or irritable mood, accompanied by somatic and cognitive changes that affect the individual's capacity to function (APA, 2013, p. 155).
DEMENTIA
Dementia is characterized by a decline in cognition that typically affects multiple cognitive domains such as memory, CB1 receptors are found throughout the central nervous system, and the endogenous cannabinoid system is thought to be important in the regulation of synaptic transmission (Baker et al., 2003), a process that is disordered in patients with dementia.
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FDA Approves First Drug Comprised of an Active Ingredient Derived from Marijuana to Treat Rare, Severe Forms of Epilepsy
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